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Future research should focus on developing strategies for selective targeting to minimize effects on normal tissues, understanding mechanisms of resistance and ways to overcome them, and optimizing combination therapies with chemotherapy, radiotherapy, or immunotherapy to enhance efficacy

Yan Y, Gong Y, Jiang M, Gao Y, Guo S, Huo J, et al

Abstract Colorectal cancer (CRC) is one of the most common malignancies and the second leading cause of cancer-related death worldwide

Treatment protocols are individualized and monitored under provider supervision to ensure safety, tolerability, and appropriate clinical oversight

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Dosing frequency: Oral semaglutide is daily