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10.1152/ajpcell.00046.2015 Am J Physiol Cell Physiol

Erianin shows a multi-target anticancer mechanism in the treatment of bladder cancer (65)

Notably, while total FOXO4 protein levels remained consistent between young and elderly men, a striking age-dependent shift in its subcellular localization was observed: FOXO4 predominantly resided in the cytoplasm in young Leydig cells but translocated to the nucleus in aged cells