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According to the SmPC, the most frequent side effects include: Nausea : Very common (may affect more than 1 in 10 people), particularly during dose initiation or escalation

Why Side Effects Vary Between Patients Every patients genetic blueprint is unique

If more than 5 days late, skip the missed dose and resume as planned

Evening dosing lets you sleep through mild queasiness

Consistency in timing, while not strictly required, helps establish a habit and reduces the likelihood of forgotten doses