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To compare the frequency difference between groups, the chi-squared test or Fischers exact test was used

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Research reveals that IGF-1 facilitates tendon regenerative healing by modulating inflammatory responses, promoting tenocyte proliferation and migration, enhancing collagen productionparticularly type I collagen which comprises the primary structural component of tendon tissueand inducing appropriate cell differentiation during the repair process

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NF - B pathway: inhibits NF - B p65 nuclear translocation, reduces I B phosphorylation, blocks osteoclast activation and bone resorption function

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