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The structural modifications incorporated into CJC-1295 include D-alanine at position 2 to enhance resistance to enzymatic degradation, glutamine at position 8 to reduce asparagine rearrangement and prevent amide hydrolysis to aspartic acid, alanine at position 15 to enhance bioactivity, and leucine at position 27 to prevent methionine oxidation

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It has not been evaluated by the FDA, and no therapeutic or diagnostic application is implied or permitted

Obesity 14 , 15531561 (2006)

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