The best phytonutrient foods are colorful, whole plant foods, including berries, leafy greens, cruciferous vegetables, tomatoes, carrots, sweet potatoes, citrus fruits, herbs, spices, garlic, onions, legumes, nuts, seeds, whole grains, tea, coffee and cocoa
It can turn on survival promoting signaling cascades, amplify inflammation, act mitogenetically against therapy-induced oxidant pressure, or stimulate ferroptosis, a non-apoptotic necrotic-like morphing of deceased cells marked by iron-dependent lipid peroxidation [16, 21,22,23]
The combination is described in pharmacology literature as synergistic
Pyocyanin, being a zwitterion, diffuses across the host cell membrane and undergoes redox reactions by accepting electrons from NADPH which it subsequently donates to molecular oxygen to form primarily O 2 - and subsequently H 2 O 2 through dismutation ( The results detailed in Figure 5 provide a means to explain the pyocyanin/GPx/GRed/GSH interplay: that is, pyocyanin increases the level of ROS, and this leads to enhanced GPx activity in A549 cells because GPx catalyzes the reaction through which GSH neutralizes H 2 O 2
Being able to identify medications correctly is important to ensure that patients are taking the right drug and dose
The recommended use level is 2-5% according to the manufacturer
