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Protocol 4: the medication transition plan Goal: Switch between GLP-1 medications without losing coverage or creating dangerous overlap Schedule (example: tirzepatide to semaglutide): Take last tirzepatide dose on day 0 Begin semaglutide at starting dose (0.25 mg) on day 7 Follow standard semaglutide escalation from there Why the plotter supports this: The plotter shows that seven days after your last tirzepatide dose, approximately 38% remains in your system

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A much higher percentage of people taking tirzepatide reached the target A1c of less than 7% (the goal for many with diabetes) compared to those on semaglutide

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