C2C12 myotube cells treated with palmitic acid (PA) were divided into four groups: control group, PA group, PA + LIRA group, PA + SEMA group
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Exclusion criteria included non-English language studies, books, conference papers, case reports, in vitro studies, animal studies, and non-original articles
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A long half-life of roughly 6 days makes a single weekly subcutaneous injection practical, while gradual titration keeps tolerability high from the first dose [1] [4]