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C2C12 myotube cells treated with palmitic acid (PA) were divided into four groups: control group, PA group, PA + LIRA group, PA + SEMA group

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Exclusion criteria included non-English language studies, books, conference papers, case reports, in vitro studies, animal studies, and non-original articles

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**Please note that the information provided in this podcast is not intended to be a substitute for professional medical advice, diagnosis or treatment that can be provided by your own Medical Doctor

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A long half-life of roughly 6 days makes a single weekly subcutaneous injection practical, while gradual titration keeps tolerability high from the first dose [1] [4]

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