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Beyond 8 weeks: Most side effects significantly diminish or resolve after two to three months of treatment

This typically appears within the first few applications and resolves within one to two weeks of continued use

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Many people report that the hardest period is days 14 through 21, when the drug levels have dropped enough for appetite to return noticeably but not enough time has passed for new habits to feel automatic

For instance, a study published in The Journal of Nutritional Biochemistry found that overweight individuals affected with diabetes mellitus or impaired fasting glucose who consumed 40 grams of whey protein a day saw an increase in glutathione peroxidase (9)