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Sies H, Stahl W, Sevanian A, Nutritional

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Grade A evidence includes multi-center cohort studies and meta-analyses with large sample sizes providing the strongest evidence base (81)

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A couple of commenters recommended CMS minimize the number of data elements for covered entities to submit to the repository

The Raun 1998 study compared ipamorelin head-to-head with GHRP-2 and GHRP-6 in rats and found that at doses producing equivalent GH release, ipamorelin caused no statistically significant increase in cortisol or prolactin, while GHRP-2 and GHRP-6 produced significant elevations of both