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RNA quantity and integrity were analyzed with Nanodrop (Thermo Fisher Scientific, Wilmington, DE) and Nano chip for Eukaryotes on the Agilent 2100 Bioanalyzer (Agilent Technologies, Santa Clara, CA)

ALCAR limits PCa induced pro-angiogenic features and regulates CXCL8-CXCR1/2, CCL2-CCR2 and CXCL12-CXCR4 axis in endothelial cells The vascular endothelial growth factor (VEGF) and CXCL8, a CXC inflammatory chemokine, have been demonstrated to induce angiogenesis and promote progression of PCa [44, 45]

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33 With an intact aortal cushioning function, the PWV is slow, and the reflected wave returns in diastole, contributing to coronary perfusion

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