Contraindications:: Patients with a personal or family history of medullary thyroid carcinoma (based upon animal data - see FDA Warning) History of hypersensitivity to semaglutide or any of its excipients (serious reactions including angioedema & anaphylaxis have been reported) Side Effects: GI Adverse events: nausea, vomiting, constipation, diarrhea (~5-15%) most GI side side effects occur during dose initiation or escalation and wane after a few weeks (Drucker, 2024)
Regulatory and market barriers: Reluctance from pharmaceutical companies to invest in costly trials and difficulties in demonstrating superiority over conventional therapies impede commercialization (54)
Painter JN, Anderson CA, Nyholt DR, Macgregor S, Lin J, Lee SH, Lambert A, Zhao ZZ, Roseman F, Guo Q, Gordon SD
Maddalena, G, Zeineddine, F, Chowdhury, S, Zeineddine, MA, Yousef, A, Bergamo, F, Lonardi, S, Yap, TA, White, MG, Overman, MJ, Kopetz, S , Shen, JY
Its one of four fat-soluble vitamins, which means your body stores it in fat cells for later use
*Hair, skin & nails: Biotin and Zinc contribute to the maintenance of normal skin, hair and nails
