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5 Conclusion Oxidative stress and inflammatory factors play crucial roles in endometriosis

Pathophysiology of varicoceles in male infertility

3.4.1 Sperm protein biomarkers Due to their inability to engage in de novo protein synthesis, the functional maturation of human spermatozoa is reliant on changes associated with two phases of post-testicular maturation, namely: (i) the incorporation of new proteins encountered during their descent through the male reproductive tract (epididymis), and (ii) the processing and/or post-translational modification of their intrinsic proteome that occurs during post-ejaculatory capacitation (57) ( Figure 2 )

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