Food Sci Nutr 2021, 9 (5), 27332742
Bibcode:2013JBiCh.28826480L
The amygdala, the hippocampus and the hypothalamus are the brain regions with the highest concentration of vitamin C, but even in these structures the distribution is not homogeneous (Mefford et al., substantia nigra is the brain region with the lowest concentration of ascorbate (Grmewald, Vitamin C and neuronal differentiation, maturation, and survival The effect of ascorbate on the differentiation of embryonic stem cells into neurons in vitro is associated with an increase in the expression of genes involved in this process (Harrison and May, in vitro due to the potentiating effect of 2-glucoside-L-ascorbic acid (ascorbate analog) on the nerve growth factor (NGF) has also been shown
In 2020, Trulicity also received FDA approval for the reduction of cardiovascular risk in adults with type 2 diabetes
It is not a generic version of either brand, because neither Wegovy nor Ozempic has an approved generic equivalent
Crucially, NICE emphasises that medication should be prescribed only as part of a multicomponent intervention that includes dietary advice, physical activity guidance, and behavioural strategies
