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SKU: 56587088888

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Description

Expression of Akt1/2 , Irs1/2 and Insr , as well as several transcription factors important in adipocyte metabolism and function such as Pparg , Foxo1 , Cebpb and Tcf7l2 were reduced in adipose Ndufs2 KO mice

doi: 10.3390/biomedicines10123130

The intraperitoneal route was selected to ensure reliable dosing and consistent systemic exposure, as ROSU exhibits low oral bioavailability (approximately 20%) (Hanke et al