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For instance, berberine, a natural compound, downregulates the expression of SLC1A5 in Hep3B and BEL-7404 cells, inhibiting Gln uptake and consequently suppressing expansion of liver cancer cells and tumor progression in vivo (77)

Honda et al.s study incorporated lifestyle interventions such as diet and exercise alongside GSH, which introduces confounding variables that obscure the potential independent effects of GSH on liver function [101]

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