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Understanding disease heterogeneity enables precision medicine approaches

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Healthcare providers carefully monitor patients' progress throughout the treatment period, adjusting protocols as needed for optimal results

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The most common SNVs, which are even found in pre-neoplastic nevi 1,2,3 , constitutively activate the BRAF kinase or NRAS GTPase, although deleterious SNVs that impair tumour suppression by NF1 are also frequently detected 4,5