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Una vez activadas las vas reparativas, persisten 24-72 h independientemente de la presencia plasmtica del pptido
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GLP-1RAs are generally recommended for patients with T2D whose glycated haemoglobin (HbA 1c ) is above target despite diet, exercise and existing glucose-lowering medication, and GLP-1RAs with proven cardiovascular benefit are also recommended in patients with T2D at elevated cardiovascular risk, regardless of HbA 1c [5, 6]
It then plays a significant role in signaling tissue remodeling which removes damaged/scarred tissue and generates new, healthy tissue
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The step-wise progression exists because higher doses produce stronger appetite suppression and metabolic effects, but also increase the likelihood of side effects like nausea or gastrointestinal discomfort
doi: 10.1104/pp.104.045724
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