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If your family history includes medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2), GLP-1 therapy is contraindicated because these medications stimulate thyroid C-cells, raising cancer risk

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Use only in qualified laboratory environments with institutional oversight

Not because of a drug interaction, but because the hours immediately following injection are when nausea is most likely

Conclusion Bupropion provides a unique combination of benefits for patients who have depression, seasonal affective disorder, obesity, or nicotine dependence