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Collectively, these observations suggest that in the immature ISCs, CFTR activation may promote a proliferative state and potentially drives differentiation into mature adult-type enterocyte precursors, subsequently affecting the functional maturation of the intestinal epithelium

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Serena Williams Using the GLP1 drug, the tennis great Serena Williams announced in summer 2025 that she shed 31 pounds (lb) after having her second child