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Diet and exercise must be considered as the first line of treatment, however if they fail to correct metabolic signalling, IGF-1 therapy seems to be promising at metabolic harmonisation

The first randomized, double-blind, placebo-controlled trial using liraglutide after MBS was performed by Lofton et al

As personalized care becomes a central focus in healthcare, these medications provide new hope for individuals battling obesity and type 2 diabetes

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Its level decreases with age (especially from the age of 45-50) and as the body's defence needs increase (immunity, liver detoxification, antioxidant defences...)