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Any uncontrolled series will capture that effect and attribute it to the drug

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Semaglutide is a GLP-1 receptor agonist that mimics the glucagon-like peptide-1 hormone, playing a crucial role in appetite regulation and glucose metabolism

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In ferroptosis-sensitive cells, TfR1 expression is upregulated, enhancing iron uptake, while ferritin heavy chain (FTH1) and ferritin light chain (FTL) undergo selective degradation via ferritinophagy (Santana-Codina and Mancias, 2018