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In a rabbit ear scar model, the HA/VP-PLA treatment group showed a significantly reduced scar elevation index of approximately 3550% compared to the control group, and excessive tissue hypertrophy was markedly alleviated
General Section, 98 (1), 1-13
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To further characterize these interactions, we constructed a molecular interaction network (Figure 7C) revealed three functionally interconnected modules: ( Consistent with multi-omics findings, KEGG pathway analysis identified glutathione metabolism as the most significantly perturbed shared pathway (Figure 8A), exhibiting coordinated changes between upregulated antioxidant enzymes such as Gpx3 and Mgst1 alongside depleted glutathione derivatives, supporting redox imbalance as a key pathogenic feature
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