The timing of dox or cisplatin treatment is indicated as Day 0 by a dark blue line, with lighter dashed lines for subsequent 50-day increments
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Beyond classic bone-marrow suppression and transaminase elevation, four pulmonary-specific and systemic hazards demand particular vigilance in patients with LC: Radiation-like pneumonitis/fibrosis, iron-catalyzed oxidative stress, CD8+ T-cell functional exhaustion and QT-interval prolongation (144)
4 Djillani et al., Review (TREK-1 / spadin)Review of TREK-1 (KCNK2) as an antidepressant target and the development of spadin-derived peptides such as PE-22-28
Available from: WeightWatchers-to-Acquire-Sequence-a-Digital-Health-Platform-for-Clinical-Weight-Management 17 Landi, H., 2023