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When HLS rats were treated with IGF-1/BP3 (50 mg/kg, b.i.d.), they retained greater body and muscle mass

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As demonstrated in formulations of heparin and low-molecular-weight heparin, pulmonary delivery showed comparable bioavailability to subcutaneous administration 67

Intramuscular fat infiltration decreased, suggesting better muscle quality

To create a time-course, 10 L aliquots were removed at 30-s intervals over a 10-min period and added to separate reaction tubes pre-aliquoted with 200 mM phosphoric acid to terminate the reaction

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