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Abstract Many local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation

Key Mediators Cytokines Since the discovery of IL-1 and TNF, extensive characterisation of their biological and physicochemical properties has enabled production of recombinant proteins

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GHK-Cu sometimes used topically at wound site alongside systemic BPC-157

PLoS ONE 15:e0235335 Katahira I, Neo S, Nagane M, Miyagi S, Hisasue M, Bhuyan AAM (2020) Characterization of suicidal erythrocyte death (eryptosis) in dogs