Inhibition of drug-metabolizing enzymes by fluorinated quinolones has been described in human medicine and for both enrofloxacin and marbofloxacin in animals
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A prospective, double-blind, Class II RCT study totaling 239 patients with chemotherapy-induced peripheral neuropathy tested the effect of oral administration of ALC 3 g/day
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There is no good quality clinical evidence to suggest that a reduction in sulphotransferase activity affects paracetamol metabolism or increases the risk of paracetamol toxicity (see Table 1 in the supplementary data for a summary of the evidence and see Fig