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F., Karevicius, S., Malsch, M., Sarda, V., Fadayomi, A., Harris, H

Additionally, the long-term safety of ferroptosis inhibitors in IgA nephropathy is unevaluatedprolonged inhibition may promote tumorigenesis or exacerbate fibrosis, risks that require rigorous assessment in long-term preclinical models

A common thread uniting all key enzymes and metabolites that combat lipid peroxidation during ferroptosis is a dependence on a key cellular reductant, nicotinamide adenine dinucleotide phosphate (NADPH)

doi:10.1016/j.cmet.2022.09.018

A., & Robble, M

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