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With a lower list price, the rebate tradeoffs tied to those strategies may be smaller, which may change the cost-benefit balance for some plan sponsors and open the door to additional strategies

Concerns exist regarding effects on existing moles and potential melanoma risk, though causality has not been established

This growing body of evidence hints at the potential for GLP-1 drugs to play a role in migraine management

In the head-to-head SURMOUNT-5 trial (NEJM 2025) tirzepatide produced larger mean body-weight reduction than semaglutide (20.2% vs 13.7% at 72 weeks), although semaglutide carries the broader cardiovascular- and kidney-outcomes dataset to date

Compound: Ipamorelin 5mg