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The president first pushed the idea of forcing drug companies to match prices offered abroad during his previous term, but faced significant resistance from the industry, including pushback in a lawsuit that resulted in a federal court order blocking his administration from carrying the plan out because it had failed to follow proper regulatory procedures
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Interestingly, alcohol administration caused a rather selective activation of NADPH oxidase (NOX), which, in turn, enhanced levels of reactive oxygen species (ROS) and 4-hydroxynonenal, but these were predominantly localized in astrocytes and microglia
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In contrast, patients with mild GO are usually treated only with local methods (88)
