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Food & Drug Administration (2021) FDA approves first generic of once-daily GLP-1 injection to lower blood sugar in patients with type 2 diabetes, U.S

The delivery method, whether injection, sublingual , or troche , does not change this outcome

Dry mouth is a less discussed but frequent complaint

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Common Adverse Effects of GLP-1s The most common adverse effects of GLP-1 receptor antagonists 26 are gastrointestinal-related, including: Nausea Diarrhea Vomiting Constipation Abdominal pain Dyspepsia/indigestion (upset stomach) Nausea is the most common of the GI symptoms, affecting up to 50% of users, but the frequency often gradually reduces as therapy continues

Blood-Brain Glucose Transfer in Alzheimers Disease: Effect of GLP-1 Analog Treatment. Scientific Reports, vol