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411 Additionally, mononuclear cell proteins in the blood of -thalassemia patients have increased binding activity with oligonucleotide probes targeting Nrf2-associated antioxidant response elements (ARE), 411 suggesting an adaptive survival response to oxidative stress in these patients

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The proteins were purified from cell culture supernatant using a human albumin affinity column, followed by size exclusion chromatography (SEC), which yielded monomeric fractions that migrated on non-reducing sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) gels according to their molecular weight (MW) (66.5 kDa) (Fig

As the body breaks down hemoglobin, the color shifts through green and yellow before fading

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