Properties: The drug is a combination of two hypoglycemic drugs with complementary mechanisms of action, designed to improve glycemic control in patients with type 2 diabetes mellitus: sitagliptin, an inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), and metformin, a representative of the biguanide class
Performance degradation may not be visually apparent
Delaying dose escalation by one week is recommended if side effects are intolerable at a given dose level
GLP-1 and amylin-mediated reductions in food intake produce weight loss that includes both fat and lean mass, with the ratio dependent on protein intake, physical activity, and the magnitude of caloric deficit
Post-Exertional Malaise (PEM) and Fatigue: By healing the gut lining and reducing the chronic, low-grade systemic endotoxemia caused by leaky gut, the body expends significantly less cellular energy fighting constant inflammation, preserving vital ATP for daily physical and cognitive function
But then I have to go from biology to chronic relapsing disease