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The following skin parameters were recorded: hydration (corneometer), TEWL (tewameter), desquamation (standard D-Squame disc), wrinkles (trained dermatologist grading scale and PRIMOS 3D imaging system), and elasticity (ballistometer) at 4, 8, and 12 weeks

Evidence-based lifestyle interventionsincluding structured dietary advice, physical activity programmes, and psychological supportshould be explored as first-line approaches

Weight loss with metformin Metformin is a first-line medication for controlling blood glucose (sugar) levels in people with type 2 diabetes

S-Acetyl-L-Glutathione is a stabilized form of glutathione, thereby maximizing its absorbency and effectiveness

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CaloriBurnis a branded, ultra-concentrated Grains of Paradise (Aframomum melegueta) extract designed to activate Brown Adipose Tissue (BAT) to promote thermogenesis and fat burning