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Despite low CNS penetration, some studies report detectable levels in the brain, supporting its potential for systemic biological effects without significant accumulation (Jzwiak et al

In comparison with other standard treatments it is more effective for ulcers and various wounds, and can be used without a carrier needed for other peptides, both locally and systemically (i.e., perorally, parenterally)

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Scar tissue or lipohypertrophy areas should be avoided

Many people look to NAD+ support, such as Liposomal NAD+, to help maintain these levels