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Crocin caused relaxation in rings precontracted with phenylephrine in a dose-dependent manner but not in KCl-precontracted aortic rings

As a dual amylin and calcitonin receptor agonist (DACRA), Cagrilintide engages both amylin and calcitonin receptors, amplifying its therapeutic potential

Overall, the core molecular machinery of ferroptosis is regulated by various cellular signalling pathways and genes but is primarily mediated through two main pathways, namely, extrinsic or transporter-dependent pathways (e.g., reduced cysteine or glutamine uptake and increased iron uptake) and intrinsic or enzyme-regulated pathways (e.g., inhibition of glutathione (GSH) peroxidase 4 (GPX4) antioxidant system) (Fig

Furthermore, these two pathways are vital components of both the AD-related pathway-gene network and the natural product-gene-pathway networks

Name of the approval committee: The Ethics Committee of the First Affiliated Hospital of Jinan University

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