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Most episodes were mild to moderate, and the median duration of individual nausea episodes was approximately 8 days
The researchers attributed the edge to mechanism: the improved performance is likely linked to tirzepatide's dual mechanism of action: whereas semaglutide works by activating receptors for GLP-1, tirzepatide mimics not only GLP-1 but the additional hormone GIP
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Some of these include hormone replacement therapy (HRT), which can balance hormones that may be contributing to hot flashes
du Bois-Reymonds Arch Anat Physiol
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