triumph 1 trial retatrutide produces up to 30.3% weight loss in Phase 3 Retatrutide Achieves Large Weight Decreases

From what I've learned, and even seen directly on Zepbound packaging, the concentration can fluctuate, meaning the amount of drug per millilitre (mg/mL) isn't always the same across different doses or even different brands

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There was also an increase in the median (IQR) of the Bristol stool scale indicating that the stools were softer

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Here's what SURMOUNT-5 found in 751 adults with obesity (without type 2 diabetes) over 72 weeks: Tirzepatide group: Average weight loss of 20.2% Semaglutide group: Average weight loss of 13.7% That's a meaningful difference roughly 6.5 percentage points