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A 140 is less so, with an increasing ratio of A 142 to A 140 leading to increased oligomerization and toxicity, possibly due to the inhibitory effect of the A 140 isoform (Qiu et al., 2015

When administered subcutaneously near the abdomen, the peptide migrates to sites of tissue injury via systemic circulation, binding to growth factor receptors that initiate angiogenesis (new blood vessel formation) and collagen synthesis

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