They can be easily recognized by primary care physicians by their multiple complaints, negative physical examination results, and a history of multiple medical examinations . Now, lets consider the level of rigor by which people with unexplained symptoms have been examined in the past
If you are mildly B12 deficient but are otherwise in good health, you may be able to raise your B12 levels with a few simple dietary adjustments
Supplementation with trimethylglycine (betaine) at 12g daily or SAMe (S-adenosylmethionine) at 400800mg daily can offset potential methyl donor depletion
Full trial-reported timeline by phase and use case
A patient info leaflet advises women to tell clinicians if pregnant, but also notes supplementing prevents deficiency risks
Gastrointestinal conditions such as celiac disease, Crohns disease or surgical changes like gastric bypass Older adults who may have reduced B12 absorption People who follow a strict vegetarian or vegan diet, as B12 is mainly found in animal-based foods People taking medications like PPIs or metformin or those with folate deficiency Real reddit experiences Below are some first-hand accounts from Reddit users: I was diagnosed with pernicious anemia after months of fatigue and neuropathy