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Patients should be offered this alternative after an informed discussion on the advantages and disadvantages of both treatment options. oral vitamin B12 is an effective alternative to vitamin B12 IM injections Cochrane Review

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The reduction in glycemic biomarkers had an independent effect on the neuroprotective benefits of the diets and therefore, glucose control may play a major role in attenuating neurodegeneration, with polyphenols having an additive benefit