In addition, quercetin has been reported to exert similar protective effects by activating the Nrf2/HO-1 signaling pathway, enhancing antioxidant enzyme expression, and mitigating hydrogen peroxide-induced oxidative stress in keratinocytes (Jafarinia et al., 2020)
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Given its high usage and availability as an over-the-counter analgesic, a systematic review of paracetamols efficacy and tolerability in individual conditions is warranted (Roberts et al., 2016)
Prostanoids in health and disease
Antioxidants essentially help counteract this normal exchange between cells and free radicals and help to lessen its damaging effects
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