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This slower gastric transit, combined with reduced food intake and often lower fluid consumption, can lead to constipation in 1530% of users

Extracted total RNA samples (1 g) were reverse transcribed using the High-Capacity cDNA Reverse Transcription Kit (Thermo Fisher Scientific, Waltham, MA, USA)

Arguably, the absence of IL-6 fails to eradicate Th17 cells, indicating that other factors can compensate for its role [34]

These injections deliver a concentrated dose of vitamins and minerals directly into the bloodstream, bypassing the digestive system

4 Discussion Our study spearheads a systematic assessment of gastrointestinal adverse event risks for GLP-1 receptor agonists and multi-target agonists in type 2 diabetes patients, addressing a critical gap in comparative safety data via Bayesian network meta-analysis