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A large electronic health record cohort study found that patients who used phentermine beyond three months did not show increased cardiovascular adverse events, including no elevated risk of heart attack, stroke, or death over three years of follow-up

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We use experimentally determined forms for these allosteric interactions but sometimes the details of the kinetics are not known, forcing us to make reasonable educated guesses

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Cantelli M, Ferrillo M, Granger C, Fabbrocini G