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doi: 10.1002/ijc.31219

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SLE patients also have lower hematocrit levels compared to healthy individuals and exhibit a higher percentage of PS-exposing erythrocytes, elevated cytosolic Ca 2+ levels, abundance of ROS, and significant erythrocyte shrinkage [327, 328]

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Furthermore, SFN orchestrates a multi-pronged assault on cancer cells by promoting the acetylation of non-histone proteins such as p53, and synergistically activating critical pathways including cell cycle arrest, apoptosis, and sensitization to other therapeutic agents like TRAIL, which is particularly promising for targeting therapy-resistant cases (66)