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While biotin deficiency is rare as our body only requires very tiny amounts, it is essential for the metabolism of fat

Wanitphakdeedecha R, Manuskiatti W, Siriphukpong S, Chen TM

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3c), compounds 1 - 5 were found to be slow inhibitors as they displayed little to no inhibition after 15 min, but time-dependent inhibition of TGR over 25 h (Fig