A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)
Baric I, Zschocke J, Christensen E, Duran M, Goodman SI, Leonard JV, Muller E, Morton DH, Superti-Furga A, Hoffmann GF: Diagnosis and management of glutaric aciduria type I
Maebashi M, Kawamura N, Sato M, Imamura A & Yoshinaga K (1978): Lipid-lowering effect of carnitine in patients with type-IV hyperlipoproteinaemia
The lean mass problem with GLP-1 receptor agonists is real and well-documented
whereas at 13 weeks, enhanced brain cell damage was suggested by reduced fission and autophagosome markers, as well as increased apoptosis and DNA fragmentation markers, which were partially reversed by maternal L-Carnitine supplementation
Despite this, the concentrated formula provides excellent value for those who require a stronger dosage