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When to slow down the titration The trial protocols were designed for average responses

Methods Data Source EHR and prescription data were extracted from the IBM Explorys EHR database (IBM Watson Health, Armonk, NY, USA), allowing clinical outcomes to be linked to treatment use

Severe kidney disease (eGFR below 30 mL/min/1.73m) represents a relative contraindication requiring specialist input

On paper, you shouldnt need an electrolyte supplementif you have the perfect diet

Intravenous infusion of GLP-1 induces diuresis and natriuresis Intravenous infusion of GLP-1 increased urine flow and sodium excretion in both Sham and HF rats

Ethics declarations Ethics approval All patient data accessed by the researchers were fully pseudonymized