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Metabolic bariatric surgery (MBS) is increasingly recommended for adults with a body mass index (BMI) 40 kg/m 2 , regardless of comorbid conditions, or a BMI 35 kg/m 2 in the presence of metabolic T2DM, uncontrolled hypertension, or MASLD [6,196]

By adhering to these guidelines, you can safely integrate exercise into your lifestyle while taking semaglutide, amplifying its benefits for weight loss and overall health

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Rather than changing the DNA sequence itself, methylation influences whether certain genes are switched on or off, allowing different cells to perform specialised functions despite containing the same genetic information