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Hussain SP, Amstad P, He P, Robles A, Lupold S, Kaneko I, Ichimiya M, Sengupta S, Mechanic L, Okamura S, Hofseth LJ, Moake M, Nagashima M, Forrester KS, Harris CC (2004) p53-Induced Up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis

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This may partially explain why no significant associations have been found between homozygosity for the MTHFR thermolabile defect or heterozygosity for mutations in the CBS gene and cardiovascular risk (Folsom et al, 1998

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